3 products were found matching "1416334-69-4"!

No results were found for the filter!
GSK-A1
GSK-A1

Item number: TGM-T27499-1mg

Description: GSK-A1 is a specific inhibitor of PI4KA, also inhibited calcium-driven PRL secretion without affecting calcium signaling and Prl expression. GSK-A1 has anti-hepatitis C virus (HCV) potential. Target: HCV Protease, PI4K. Smiles: COc1ncc(cc1S(=O)(=O)Nc1ccccc1F)-c1ccc2nc(N)n(-c3ccc(cc3)N3CCOCC3)c2c1....
Application: PI4KIIIalpha inhibitor
CAS 1416334-69-4
MW: 574.63 D
From 72.00€ *
Review
GSK-A1
GSK-A1

Item number: SYN-1219-M001

Solid. Soluble in DMSO. GSK-A1 is a potent PI4KA inhibitor with an IC50 of about 3nM in vitro using HEK-AT1 cells. Phosphatidylinositol 4-kinase type III? (PI4KA) is a host factor essential for hepatitis C virus replication and hence is a target for drug development. RNAi studies have shown that PI4KA is a mandatory...
Keywords: 5-(2-Amino-1-(4-morpholinophenyl)-1H-benzo[d]imidazol-6-yl)-N-(2-fluorophenyl)-2-methoxypyridine-3-sulfonamide, GSKA1
Application: Potent PI4KA inhibitor
CAS 1416334-69-4
MW: 574,6 D
From 185.00€ *
Review
GSK-A1
GSK-A1

Item number: Cay34502-1

GSK-A1 is an inhibitor of phosphatidylinositol 4-kinase IIIalpha (PI4KIIIalpha, IC50 = 3.16 nM). It is selective for PI4KIIIalpha over PI4KIIIbeta, PI3Kalpha, PI3Kbeta, and PI3Kdelta (IC50s = >50 nM) but also inhibits PI3Kgamma (IC50 = 15.8 nM). GSK-A1 decreases the levels of phosphatidylinositol 4-phosphate...
Keywords: 5-[2-amino-1-[4-(4-morpholinyl)phenyl]-1H-benzimidazol-6-yl]-N-(2-fluorophenyl)-2-methoxy-3-pyridinesulfonamide
Application: PI4KIIIalpha inhibitor
CAS 1416334-69-4
MW: 574.6 D
From 41.00€ *
Review