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ABT-751
Item number: TGM-T1758-100mg
Description: ABT-751 (E7010) has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer. Target: Microtubule Associated, Autophagy. Smiles: COc1ccc(cc1)S(=O)(=O)Nc1cccnc1Nc1ccc(O)cc1. References: Meany HJ, et al. Pediatr Blood Cancer. 2010, 54(1), 47-54.
| Keywords: | E7010 |
| Application: | Microtubule polymerization inhibitor |
| CAS | 141430-65-1 |
| MW: | 371.41 D |
From 42.00€
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ABT-751
Item number: Cay22935-10
ABT-751 is a tubulin polymerization inhibitor that binds to the colchicine binding site on beta-tubulin (Ki = 3.3 µM). It inhibits tubulin polymerization in a concentration-dependent manner and inhibits growth of 26 human tumor cell lines (IC50s = 0.06-0.08 µg/ml). ABT-751 (100 mg/kg, p.o.) induces tumor regression...
| Keywords: | N-[2-[(4-hydroxyphenyl)amino]-3-pyridinyl]-4-methoxy-benzenesulfonamide |
| Application: | Microtubule polymerization inhibitor |
| CAS | 141430-65-1 |
| MW: | 371.4 D |
From 111.00€
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