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KT109
Item number: TGM-T27752-2mg
Description: KT109 is a selective inhibitor of DAGLbeta (IC50 = 42 nM). KT109-treated wild-type mice displayed reductions in LPS-induced allodyni as well as in DAGL-beta (-/-) micea. Repeated KT109 administration prevented the expression of LPS-induced allodynia, without evidence of tolerance. Intraplantar injection...
| Keywords: | KT-109, KT 109 |
| Application: | DAGLB inhibitor |
| CAS | 1402612-55-8 |
| MW: | 422.52 D |
47.00€
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KT109
Item number: Cay18933-1
In humans, two forms of diacylglycerol lipase, DAGLalpha and DAGLbeta, generate the endocannabinoid 2-arachidonoyl glycerol (2-AG, Cay-62160) by attacking DAG at the sn-1 position. KT109 is a selective inhibitor of DAGLbeta with an IC50 value of 42 nM. It demonstrates ~60-fold selectivity for DAGLbeta over...
| Keywords: | (4-[1,1'-biphenyl]-4-yl-1H-1,2,3-triazol-1-yl)[2-(phenylmethyl)-1-piperidinyl]-methanone |
| Application: | DAGLB inhibitor |
| CAS | 1402612-55-8 |
| MW: | 422.5 D |
From 60.00€
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