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TUG-770
TUG-770

Item number: TGM-TQ0241-100mg

Description: TUG-770 is a GPR40/FFA1 agonist with potential anti-inflammatory activity.TUG-770 can be used to study type 2 diabetes, dementia, and Alzheimer's disease. Target: GPR. Smiles: OC(=O)CCc1ccc(cc1F)C#Cc1ccccc1CC#N. References: Christiansen E, et al. Discovery of TUG-770: A Highly Potent Free Fatty Acid...
Keywords: TUG 770, TUG770
Application: GPR40 agonist
CAS 1402601-82-4
MW: 307.32 D
From 58.00€ *
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TUG-770
TUG-770

Item number: Cay22131-1

TUG-770 is an agonist of free fatty acid receptor 1 (FFA1/GPR40, EC50 = 6.16 nM for a response to the full FFA1 agonist TUG-20 in a calcium assay in 1311N1 cells). It is selective for FFA1 over FFA2 (EC50 = 933 nM in a BRET assay). It reduces glucose levels in mice in an intraperitoneal glucose tolerance test in a...
Keywords: 4-[2-[2-(cyanomethyl)phenyl]ethynyl]-2-fluoro-benzenepropanoic acid
Application: GPR40 agonist
CAS 1402601-82-4
MW: 307.3 D
From 52.00€ *
Review