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Ibiglustat
Ibiglustat

Item number: TGM-T4473-100mg

Description: Ibiglustat (GZ402671) is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor. Ibiglustat blocks the formation of glucosylceramide (GL-1), a key intermediate in the synthesis of GL-3. Ibiglustat is potentially useful for treating Fabry disease. Fabry...
Keywords: Venglustat, SAR402671, GZ402671
Application: Targets ceramide glucosyltransferase [EC:2.4.1.80] (UGCG)
CAS 1401090-53-6
MW: 389.49 D
From 54.00€ *
Review
Ibiglustat
Ibiglustat

Item number: Cay32878-250

Ibiglustat is an inhibitor of glucosylceramide (GlcCer) synthase. Dietary administration of ibiglustat (0.03% w/w) reduces globotriaosylceramide (Gb3) and lyso-Gb3 accumulation in a variety of tissues, including the kidney, heart, and brain, in the Gla-/- mouse model of Fabry disease. It reduces the latency to paw...
Keywords: Genz-682452, GZ/SAR402671, Venglustat, N-[1-[2-(4-fluorophenyl)-4-thiazolyl]-1-methylethyl]-carbamic acid,...
Application: GlcCer synthase (ceramide glucosyltransferase) inhibitor
CAS 1401090-53-6
MW: 389.5 D
From 172.00€ *
Review