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Item number: Cay22110-5

4µ8C is an inhibitor of inositol requiring enzyme 1 alpha (IRE1alpha), which is a protein located in the endoplasmic reticulum (ER) membrane that has kinase and RNase activities triggered by ER stress. 4µ8C inhibits IRE1alpha splicing of Xbp1 mRNA (IC50 = 6.8 µM) and reduces subsequent gene expression of Erdj4 (IC50...

Keywords:	IRE1 Inhibitor III, 7-hydroxy-4-methyl-2-oxo-2H-1-benzopyran-8-carboxaldehyde
CAS	14003-96-4
MW:	204.2 D

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