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Item number: TGM-T4363-10mg

Description: CGP52432 is a very potent antagonist of GABAB receptors (IC50 = 85 nM). Target: GABA Receptor. Smiles: C(NCCCP(C(OCC)OCC)(=O)O)C1=CC(Cl)=C(Cl)C=C1. References: Bonanno G,etal.GABA(B) receptors as potential targets for drugs able to prevent excessive excitatory amino acid transmission in the spinal...

Keywords:	CGP 52432
Application:	GABA(B) receptor antagonist
CAS	139667-74-6
MW:	384.24 D

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CGP 52432

Item number: Cay27212-10

CGP 52432 is an antagonist of GABAB receptors. It selectively reverses (-)-baclofen-induced inhibition of potassium-evoked GABA release over glutamate or somatostatin release (IC50s = 0.085, 3.35, and 9.26 µM, respectively) from rat cortical synaptosomes. CGP 52432 (10 µM) reduces paired-pulse inhibition of...

Keywords:	P-[3-[[(3,4-dichlorophenyl)methyl]amino]propyl]-P-(diethoxymethyl)-phosphinic acid
Application:	GABA(B) receptor antagonist
CAS	139667-74-6
MW:	384.2 D

From 166.00€ *

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