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KN-93
Item number: TGM-T2697-100mg
Description: KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase. Target: CaMK, Autophagy. Smiles: N(S(=O)(=O)C1=CC=C(OC)C=C1)(CCO)C2=C(CN(CC=CC3=CC=C(Cl)C=C3)C)C=CC=C2. References: Tombes RM, et al. G1 cell cycle arrest and apoptosis are...
| CAS | 139298-40-1 |
| MW: | 501.04 D |
From 52.00€
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KN-93
Item number: Cay13319-1
KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase type II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). It does not affect the activities of PKA, PKC, MLCK, or Ca2+-phosphodiesterase. It inhibits histamine-induced aminopyrine uptake in parietal cells (IC50 = 300 nM). More...
| Keywords: | N-[2-[[[3-(4-chlorophenyl)-2-propen-1-yl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxy-benzenesulfonamide |
| Application: | CaMKII inhibitor |
| CAS | 139298-40-1 |
| MW: | 501 D |
From 146.00€
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