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CEP-37440
CEP-37440

Item number: TGM-T2655-100mg

Description: CEP-37440 is an effective and specific Dual FAK/ALK inhibitor with IC50s of 120 nM(ALK cellular in 75% human plasma) and 2.3 nM (FAK). Target: FAK, ALK. Smiles: CNC(=O)c1ccccc1Nc1nc(Nc2ccc3C[C@@H](CCCc3c2OC)N2CCN(CCO)CC2)ncc1Cl. References: Iragavarapu C, et al. J Hematol Oncol. 2015 Feb 27,8(1):17.
Keywords: CEP37440
CAS 1391712-60-9
MW: 580.12 D
From 32.00€ *
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CEP-37440
CEP-37440

Item number: Cay21278-25

CEP-37440 is a dual inhibitor of focal adhesion kinase 1 (FAK1, IC50s = 2.0 and 80 nM for in vitro enzyme and cellular inhibition, respectively) and anaplastic lymphoma kinase (ALK, IC50s = 3.1 and 22 nM for in vitro enzyme and cellular inhibition, respectively). It blocks the proliferation of inflammatory and...
Keywords: 2-[[5-chloro-2-[[(6S)-6,7,8,9-tetrahydro-6-[4-(2-hydroxyethyl)-1-piperazinyl]-1-methoxy-5H-benzocyclohepten-2-yl]amino]-4-...
Application: FAK1 & ALK inhibitor
CAS 1391712-60-9
MW: 580.1 D
From 49.00€ *
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CEP-37440 Hydrochloride
CEP-37440 Hydrochloride

Item number: LKT-C179603.100

Inhibitor of FAK and ALK.
Keywords: CEP-37440 Hydrochloride, CEP 37440 Hydrochloride, CEP37440 Hydrochloride
Application: FAK1 & ALK inhibitor
CAS 1391712-60-9
MW: 580.13 D
From 171.00€ *
Review