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(2R)-Octyl-alpha-hydroxyglutarate
(2R)-Octyl-alpha-hydroxyglutarate

Item number: Cay16366-10

alpha-Hydroxyglutaric acid (2-HG, Cay-16374) is normally metabolized to 2-oxoglutarate by D- and L-2-hydroxyglutarate dehydrogenases. Mutations in these enzymes cause 2-hydroxyglutaric aciduria, a neurometabolic disorder. Recent studies have found that mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2,...
Keywords: (2R)-Octyl-2-HG, 2R-hydroxy-pentanedioic acid, 1-octyl ester
CAS 1391194-67-4
MW: 260.3 D
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