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Item number: Cay34216-10

O-Demethyl apremilast is an active metabolite of the phosphodiesterase 4 (PDE4) inhibitor apremilast (Cay-18502). It inhibits the activity of PDE4 isolated from U937 cells and LPS-induced TNF-alpha production in isolated human peripheral blood mononuclear cells (PBMCs, IC50s = 8.3 and 5.6 µM, respectively)....

Keywords:	4'-hydroxy APR,...
Application:	Apremilast active metabolite, PDE4 inhibitor
CAS	1384441-38-6
MW:	446.5 D

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