4 products were found matching "138402-11-6"!
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Irbesartan
Item number: TGM-T1615-100mg
Description: Irbesartan (SR-47436) is an Angiotensin 2 Receptor Blocker whose mechanism of action involves antagonizing the Angiotensin 2 Receptor. Target: Apoptosis, RAAS. Smiles: O=C1C2(N=C(CCCC)N1CC3=CC=C(C=C3)C4=C(C=CC=C4)C=5NN=NN5)CCCC2. References: Bernhart CA, et al. J Med Chem, 1993, 36(22), 3371-3380.
| Keywords: | BMS-186295, SR-47436 |
| Application: | Targets angiotensin II receptor type 1 (AGTR1) |
| CAS | 138402-11-6 |
| MW: | 428.53 D |
From 46.00€
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Irbesartan
Item number: LKT-I6804.1
Angiotensin II type 1 receptor antagonist.
| Keywords: | Aprovel, Avapro, 2-Butyl-3-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-1,3-diazaspiro(4,4)non-1-en-4-one |
| Application: | Angiotensin II type 1 receptor antagonist |
| CAS | 138402-11-6 |
| MW: | 428,53 D |
From 76.00€
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Irbesartan
Item number: Cay11952-50
Irbesartan is an antagonist of the angiotensin II type 1 (AT1) receptor (Ki = 1.3 nM). It is an insurmountable antagonist of AT1, as its antagonism cannot be overcome by increasing concentrations of angiotensin II. Irbesartan (3, 10, and 30 mg/kg) reduces blood pressure in stroke-prone spontaneously hypertensive...
| Keywords: | BMS 186295, SR 47436, 2-butyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one |
| Application: | Angiotensin II receptor blocker |
| CAS | 138402-11-6 |
| MW: | 428.5 D |
From 61.00€
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Irbesartan
Item number: CDX-I0204-M050
Irbesartan is an orally available angiotensin II type 1 (AT1) receptor antagonist (IC50 = 1.3 nM) with antihypertensive activity. It binds to AT1 receptor with >5000 times higher affinity compared to AT2 receptor. Irbesartan also elicits selective peroxisome proliferator-activated receptor gamma...
| Keywords: | 2-Butyl-3-[[2´-(2H-tetrazol-5-yl)[1,1´-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one, Avapro, BMS-186295, SR-47436 |
| Application: | Angiotensin II type 1 (AT1) receptor antagonist |
| CAS | 138402-11-6 |
| MW: | 428,5 D |
From 122.00€
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