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Tropifexor
Item number: TGM-T4379-100mg
Description: Tropifexor (LJN452) is a novel and highly potent agonist of FXR with an EC50 of 0.2 nM. Target: Autophagy, FXR. Smiles: OC(=O)c1cc(F)c2nc(sc2c1)N1[C@H]2CC[C@@H]1C[C@@H](C2)OCc1c(onc1-c1ccccc1OC(F)(F)F)C1CC1. References: Tully DC,etal.Discovery of Tropifexor (LJN452), a Highly Potent Non-bile Acid FXR...
| Keywords: | LJN452 |
| Application: | Targets farnesoid X receptor (NR1H4, FXR) |
| CAS | 1383816-29-2 |
| MW: | 603.58 D |
From 87.00€
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Tropifexor
Item number: Cay25748-1
Tropifexor is an agonist of farnesoid X receptors (FXR). It enhances the interaction between the human FXR ligand binding domain and the steroid receptor coactivator 1 (SRC-1) peptide in a homogeneous time-resolved fluorescence (HTRF) coactivator interaction assay (EC50 = 0.2 nM). It increases expression of the FXR...
| Keywords: | LJN452,... |
| Application: | Farnesoid X receptor (FXR) agonist |
| CAS | 1383816-29-2 |
| MW: | 603.6 D |
From 114.00€
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