2 products were found matching "1380716-06-2"!

No results were found for the filter!
ML198
ML198

Item number: TGM-T8986-100mg

Description: ML198 is a novel activator and non-inhibitory chaperone of glucocerebrosidase. ML198 serves as a starting point to develop a novel approach towards small molecule treatment for patients suffering from Gaucher disease. Target: Glucokinase. Smiles: Cc1cc(C)n2ncc(C(=O)Nc3ccc(cc3)C#C)c2n1. References:...
Application: Glucocerebrosidase chemical chaperone
CAS 1380716-06-2
MW: 290.32 D
From 40.00€ *
Review
ML-198
ML-198

Item number: Cay37755-1

ML-198 is a chemical chaperone of glucocerebrosidase. It activates hydrolysis of the fluorescent glucocerebrosidase substrate 4-methylumbelliferyl-beta-D-glucopyranoside (4-MUG, Cay-20948) in spleen homogenate isolated from patients with Gaucher disease with the homozygous N370S mutant of glucocerebrosidase...
Keywords: NCGC758, N-(4-ethynylphenyl)-5,7-dimethyl-pyrazolo[1,5-a]pyrimidine-3-carboxamide
Application: Glucocerebrosidase chemical chaperone
CAS 1380716-06-2
MW: 290.3 D
From 54.00€ *
Review