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G007-LK
Item number: TGM-T6842-100mg
Description: G007-LK is a selective inhibitor of TNKS1 and TNKS2, with IC50s of 46 nM and 25 nM, respectively. Target: PARP, Wnt/beta-catenin. Smiles: CS(=O)(=O)c1ccc(nc1)-c1nnc(\C=C\c2nnc(o2)-c2ccc(cc2)C#N)n1-c1ccccc1Cl. References: Voronkov A, et al. J Med Chem, 2013, 56(7), 32012-3023.
| Application: | TNKS / TNKS2 inhibitor |
| CAS | 1380672-07-0 |
| MW: | 529.96 D |
From 45.00€
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G007-LK
Item number: Cay22934-1
G007-LK is an inhibitor of the tankyrases TNKS1 and TNKS2 (IC50s = 46 and 25 nM, respectively). It is selective for TNKS1 and TNKS2 over a panel of 90 kinases, 16 phosphatases, and 73 G protein-coupled receptors (GPCRs) when used at a concentration of 10 µM. G007-LK inhibits colony formation of COLO 320 DM and SW403...
| Keywords: | Tankyrase 1/2 Inhibitor VI,... |
| Application: | TNKS / TNKS2 inhibitor |
| CAS | 1380672-07-0 |
| MW: | 530 D |
From 44.00€
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