Description: Mafenide, a sulfonamide, inhibits the enzyme carbonic anhydrase and is used as a topical anti-infective drug, especially in burn therapy. Target: Others. Smiles: NCC1=CC=C(C=C1)S(N)(=O)=O. References: Kahn SA, Afshari A, Nguyen L, Shinha T, Huff T, Montgomery AC, Stratton C, Summitt B. Hydrofiber...

Mafenide is a sulfonamide antibiotic that inhibits growth of bacteria. It inhibits growth of clinical isolates of S. pyogenes, methicillin-susceptible S. aureus (MSSA), methicillin-resistant S. aureus (MRSA), Enterococcus, Enterobacteriaceae, and Gram-negative bacilli from burn patients in an agar well diffusion...