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SR9011
SR9011

Item number: TGM-T3688-10mg

Description: SR9011 is a REV-ERB agonist (IC50: 790 nM, REV-ERBalpha, IC50: 560 nM, REV-ERBbeta). Target: Autophagy. Smiles: CCCCCNC(=O)N1CCC(CN(Cc2ccc(s2)[N+]([O-])=O)Cc2ccc(Cl)cc2)C1. References: Solt LA, et al. Nature. 2012 Mar 29,485(7396):62-8.
Application: REV-ERB agonist
CAS 1379686-29-9
MW: 479.04 D
From 54.00€ *
Review
SR9011
SR9011

Item number: Cay11930-5

SR9011 is a REV-ERB agonist that increases the constitutive repression of genes regulated by REV-ERBalpha and REV-ERBbeta with IC50 values of 790 and 560 nM, respectively. It has no activity at other nuclear receptors. SR9011 blocks the activity of the suprachiasmatic nucleus (SCN) clock, with reversible inhibition...
Keywords: 3-[[[(4-chlorophenyl)methyl][(5-nitro-2-thienyl)methyl]amino]methyl]-N-pentyl-1-pyrrolidinecarboxamide
Application: REV-ERB agonist
CAS 1379686-29-9
MW: 479 D
From 128.00€ *
Review