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Bisindolylmaleimide III
Item number: TGM-T77628-100mg
Description: Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC), specifically interacting with PKCalpha or ribosomal S6 protein kinase 1 upon activation of these kinases. Target: PKC. Smiles: O=C1C(=C(C(=O)N1)C=2C=3C(NC2)=CC=CC3)C=4C=5C(N(CCCN)C4)=CC=CC5. References: Brehmer D, et...
| Application: | PKC inhibitor |
| CAS | 137592-43-9 |
| MW: | 384.43 D |
From 71.00€
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Bisindolylmaleimide III
Item number: Cay11072-1
Bisindolylmaleimide III was developed as a protein kinase C (PKC) inhibitor with structural similarity to the nonspecific PKC inhibitor staurosporine. At 1 µM, bisindolylmaleimide III inhibits 93% of PKCalpha kinase activity and also inhibits many other protein kinases including, S6K1, MAPKAP-K1, RSK2 and MSK1 with...
| Keywords: | BIM III, 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione |
| Application: | PKC inhibitor |
| CAS | 137592-43-9 |
| MW: | 384.4 D |
From 78.00€
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