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Item number: Cay17808-1

KP372-1 is a specific Akt inhibitor that demonstrates at least 10-fold selectivity against a panel of additional kinase targets, including CDK1, ERK1, GSK3beta, LCK, MEK1, PKA, PKC, and S6K. In acute myelogenous leukemia cells, KP372-1 is reported to inhibit the kinase activity of Akt, PDK1, and FLT3, decreasing the...

Keywords:	6H-indeno[1,2-epsilon]tetrazolo[1,5-b][1,2,4]triazin-6-one, compd. with...
Application:	Akt inhibitor
CAS	1374996-60-7
MW:	224.2 D

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KP372-1

Item number: TGM-T21964-10mg

Description: KP372-1 is an Akt inhibitor that blocks signaling through the PI3K pathway, inhibiting cell proliferation while inducing apoptosis and anoikis in squamous cell carcinoma of the head and neck. Target: Others. Smiles: O=C1c2ccccc2-c2nn3nnnc3nc12.O=C1c2ccccc2-c2nc3nnnn3nc12

CAS	1374996-60-7
MW:	448.36 D

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