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RO27-3225 (trifluoroacetate salt)
Item number: Cay41558-1
RO27-3225 is a peptide agonist of melanocortin receptor 4 (MC4R). It selectively induces cAMP production in cells expressing human MC4R (EC50 = 0.3 nM) over cells expressing MC1R, MC3R, or MC5R (EC50s = 1.1, 97.9, and 139.4 nM, respectively). In vivo, RO27-3225 (3, 5, and 10 nmol/animal) reduces food intake in rats,...
| Keywords: | Oxobutyl-His-Phe-Arg-Trp-{Sar}-NH2, N-(1-oxobutyl)-L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophyl-N2-methyl-glycinamide,... |
| Application: | Peptide MC4R agonist |
| CAS | 1373926-49-8 |
| MW: | 784.9 D |
From 35.00€
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RO27-3225 TFA
Item number: TGM-T70838-100mg
Description: RO27-3225, also known as RO273225 is a melanocortin type 4 receptor agonist with EC50 = 1 nM. It may alleviate intestinal dysfuntion and brain damage. It has been investigated for an anti-obesity medication. Ro 27-3225 shows some activity at the MC1 receptor. Ro 27-3225 reverses hemorrhagic shock,...
| CAS | 1373926-49-8 |
| MW: | 898.9462 D |
From 1,491.00€
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