3 products were found matching "1365267-27-1"!
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X-376
Item number: TGM-T3550-100mg
Description: X-376 (Ensartinib) is an orally available small molecule inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with potential antineoplastic activity. Upon oral administration, X-396 binds to and inhibits ALK kinase, ALK fusion proteins, and ALK point mutation variants. Inhibition...
| Keywords: | X-396, Ensartinib |
| Application: | ALK inhibitor |
| CAS | 1365267-27-1 |
| MW: | 547.41 D |
From 31.00€
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Ensartinib
Item number: Cay21341-1
Ensartinib is a potent and selective inhibitor of anaplastic lymphoma kinase (ALK, IC50 50 = 15 nM) but has no effect on cell growth driven by other mutant kinases or that of non-cancerous HepG2 cells. Ensartinib, at a dose of 25 mg/kg, reduces H3122 xenograft growth with no effect on body weight in nude mice. It is...
| Keywords: | 6-amino-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-N-[4-[(4-methyl-1-piperazinyl)carbonyl]phenyl]-3-pyridazinecarboxamide |
| Application: | ALK inhibitor |
| CAS | 1365267-27-1 |
| MW: | 547.4 D |
From 44.00€
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Ensartinib
Item number: LKT-E543721.100
A third-generation ALK inhibitor.
| Keywords: | X396, X-396,... |
| Application: | A third-generation ALK inhibitor |
| CAS | 1365267-27-1 |
| MW: | 547.41 D |
From 194.00€
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