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E3330
Item number: TGM-T6823-100mg
Description: E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity. Target: DNA/RNA Synthesis, HIF/HIF Prolyl-Hydroxylase. Smiles: CCCCCCCCC\C(=C/C1=C(C)C(=O)C(OC)=C(OC)C1=O)C(O)=O. References: Zou GM, et al. Blood. 2007, 109(5), 1917-1922.
| Application: | APE1/Ref-1 redox inhibitor |
| CAS | 136164-66-4 |
| MW: | 378.46 D |
From 46.00€
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E3330
Item number: Cay32830-10
E3330 is an inhibitor of apurinic-apyrimidinic endonuclease 1/redox factor-1 (APE1/Ref-1) redox activity. It inhibits APE1-mediated AP-1 DNA binding activity with an IC50 value of 6.5 µM in a redox EMSA but has no effect on APE1-mediated DNA repair activity in endonuclease or gap-filling assays when used at...
| Keywords: | APX 3330, (2E)-2-[(4,5-dimethoxy-2-methyl-3,6-dioxo-1,4-cyclohexadien-1-yl)methylene]-undecanoic acid |
| Application: | APE1/Ref-1 redox inhibitor |
| CAS | 136164-66-4 |
| MW: | 378.5 D |
From 166.00€
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