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Necrosulfonamide
Item number: TGM-T6904-100mg
Description: (E)-Necrosulfonamide ((E)-Necrosulfonamide) is an inhibitor of necroptosis. Blocks mixed lineage kinase domain-like protein (MLKL), a critical substrate of receptor-interacting serine-threonine kinase 3 (RIP3) during necrosis. Prevents MLKL-RIP1-RIP3 necrosome complex from interacting with downstream...
| Keywords: | (E)-Necrosulfonamide |
| Application: | Necroptosis inhibitor, MLKL inhibitor |
| CAS | 1360614-48-7 |
| MW: | 461.47 D |
From 52.00€
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Necrosulfonamide
Item number: Cay20844-5
Necrosulfonamide is a small molecule that inhibits necroptosis by blocking mixed lineage kinase domain-like protein (MLKL), a key substrate of receptor-interacting serine-threonine kinase 3 (RIPK3). Necrosulfonamide has been shown to prevent the MLKL-RIPK1-RIPK3 necrosome complex from interacting with downstream...
| Keywords: | (2E)-N-[4-[[(3-methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenamide |
| Application: | Necroptosis inhibitor, MLKL inhibitor |
| CAS | 1360614-48-7 |
| MW: | 461.5 D |
From 53.00€
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Necrosulfonamide
Item number: AG-CR1-3705-M005
Off-white to yellow solid. Soluble in DMSO (20mg/ml) or DMF (20mg/ml). Insoluble in water. Chemical. CAS: 1360614-48-7. Formula: C18H15N5O6S2. MW: 461.5. Inhibitor of necroptosis, by blocking mixed lineage kinase domain-like protein (MLKL), a key substrate of receptor-interacting serine-threonine kinase 3 (RIP3)....
| Keywords: | NSA, (2E)-N-[4-[[(3-methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenamide |
| Application: | Necroptosis inhibitor, MLKL inhibitor |
| CAS | 1360614-48-7 |
| MW: | 461,5 D |
From 55.00€
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