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Item number: TGM-T14357-100mg

Description: Spebrutinib besylate (AVL-292 benzenesulfonate, CC-292 besylate) is a Btk kinase activity inhibitor with an IC50 of less than 0.5 nM and a Kinact/Ki of 7.69×10^4 M^-1s^-1. Target: BTK. Smiles: O=C(C=C)NC1=CC=CC(=C1)NC2=NC(=NC=C2F)NC3=CC=C(OCCOC)C=C3.O=S(=O)(O)C=1C=CC=CC1. References: Evans EK, et al....

Keywords:	AVL-292 (benzenesulfonate), CC-292 (besylate)
Application:	Targets Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2] (BTK)
CAS	1360053-81-1
MW:	581.62 D

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