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ML228
ML228

Item number: TGM-T7836-100mg

Description: ML228 is a potent the Hypoxia Inducible Factor (HIF) pathway activator with EC50 of 1 µM. ML228 potently activates HIF in vitro as well as its downstream target VEGF. Target: HIF. Smiles: C(Nc1nc(nnc1-c1ccccc1)-c1ccccn1)c1ccc(cc1)-c1ccccc1. References: Theriault JR, et al. Discovery of a Small Molecule...
Application: HIF signaling pathway activator
CAS 1357171-62-0
MW: 415.49 D
From 37.00€ *
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ML-228
ML-228

Item number: Cay14568-1

The hypoxia-inducible factor (HIF) transcription factors are members of the basic-helix-loop-helix (bHLH) family of transcription factors and play important roles in maintaining cellular oxygen homeostasis. HIF-1alpha has emerged as an important drug target in breast and prostate cancer, cardiovascular disease, and...
Keywords: CID-46742353, N-([1,1'-biphenyl]-4-ylmethyl)-6-phenyl-3-(2-pyridinyl)-1,2,4-triazin-5-amine
Application: HIF signaling pathway activator
CAS 1357171-62-0
MW: 415.5 D
From 44.00€ *
Review