- Search results for 1357171-62-0
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2 products were found matching "1357171-62-0"!
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Item number: TGM-T7836-100mg
Description: ML228 is a potent the Hypoxia Inducible Factor (HIF) pathway activator with EC50 of 1 µM. ML228 potently activates HIF in vitro as well as its downstream target VEGF. Target: HIF. Smiles: C(Nc1nc(nnc1-c1ccccc1)-c1ccccn1)c1ccc(cc1)-c1ccccc1. References: Theriault JR, et al. Discovery of a Small Molecule...
Application: | HIF signaling pathway activator |
CAS | 1357171-62-0 |
MW: | 415.49 D |
From 37.00€
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Item number: Cay14568-1
The hypoxia-inducible factor (HIF) transcription factors are members of the basic-helix-loop-helix (bHLH) family of transcription factors and play important roles in maintaining cellular oxygen homeostasis. HIF-1alpha has emerged as an important drug target in breast and prostate cancer, cardiovascular disease, and...
Keywords: | CID-46742353, N-([1,1'-biphenyl]-4-ylmethyl)-6-phenyl-3-(2-pyridinyl)-1,2,4-triazin-5-amine |
Application: | HIF signaling pathway activator |
CAS | 1357171-62-0 |
MW: | 415.5 D |
From 44.00€
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