2 products were found matching "1357158-81-6"!
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AKT-IN-1
Item number: TGM-T4489-100mg
Description: AKT-IN-1 (AZD-26) is an allosteric AKT inhibitor (IC50: 1.04 µM). Target: Akt. Smiles: NC(=O)c1cnc(-c2ccc(cc2)C2(N)CCC2)c(c1)-c1ccccc1. References: Kettle JG, et al. Diverse heterocyclic scaffolds as allosteric inhibitors of AKT. J Med Chem. 2012 Feb 9,55(3):1261-73.
| Keywords: | AZD26, AZD-26, AZD 26 |
| Application: | AKT inhibitor |
| CAS | 1357158-81-6 |
| MW: | 343.42 D |
From 112.00€
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AZD-26
Item number: SYN-1160-M001
Soluble in DMSO or ethanol. AZD-26 is an inhibitor of AKT. AZD-26 inhibits the phosphorylation of Thr308 on AKT in BT474 cells with an IC(50) of 422nM. It also inhibits the phosphorylation of Ser473 on AKT in MDAMB468 cells with an IC(50) of 322nM. AZD-26 inhibited AKT mediated phosphorylation at ranges form 0.01µM...
| Keywords: | AZD26 |
| Application: | AKT inhibitor |
| CAS | 1357158-81-6 |
| MW: | 343,4 D |
From 256.00€
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