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ML-309 (hydrochloride)
Item number: TGM-T38004-10mg
Description: ML-309 is an inhibitor of mutant isocitrate dehydrogenase 1 (IDH1). It reversibly and selective inhibits IDH1R132H over wild-type IDH1 (IC50s = 96 and 36,500 nM, respectively). ML-309 reduces 2-hydroxyglutarate production in U87 MG glioblastoma cells (EC50 = 55 nM). Target: Others. Smiles:...
| Application: | IDH1 (R132H mutant ) inhibitor |
| CAS | 1355327-02-4 |
| MW: | 521.03 D |
From 96.00€
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ML-309 (hydrochloride)
Item number: Cay21519-10
ML-309 is an inhibitor of mutant isocitrate dehydrogenase 1 (IDH1). It reversibly and selective inhibits IDH1R132H over wild-type IDH1 (IC50s = 96 and 36,500 nM, respectively). ML-309 reduces 2-hydroxyglutarate production in U87 MG glioblastoma cells (EC50 = 55 nM).Formal Name:...
| Keywords: | N-[2-(cyclopentylamino)-1-(2-methylphenyl)-2-oxoethyl]-N-(3-fluorophenyl)-1H-benzimidazole-1-acetamide, monohydrochloride |
| Application: | IDH1 (R132H mutant ) inhibitor |
| CAS | 1355327-02-4 |
| MW: | 521 D |
From 53.00€
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