3 products were found matching "1351761-44-8"!
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GNE-7915
Item number: TGM-T1945-100mg
Description: GNE-7915 is a highly potent, selective and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) inhibitor. Target: LRRK2. Smiles: CCNc1nc(Nc2cc(F)c(cc2OC)C(=O)N2CCOCC2)ncc1C(F)(F)F. References: Estrada AA, et al. J Med Chem. 2012, 55(22), 9416-9433.
| Keywords: | GNE7915 |
| Application: | LRRK2 kinase inhibitor |
| CAS | 1351761-44-8 |
| MW: | 443.4 D |
From 40.00€
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GNE-7915
Item number: Cay16252-5
Leucine-rich repeat kinase 2 (LRRK2) is an enzyme that interacts with parkin, a ligase that is part of the ubiquitin-proteasome system that mediates the targeting of proteins for degradation. Loss of function of the parkin protein leads to dopaminergic cell death. The development of Parkinson's disease has been...
| Keywords: | [4-[[4-(ethylamino)-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2-fluoro-5-methoxyphenyl]-4-morpholinyl-methanone |
| Application: | LRRK2 kinase inhibitor |
| CAS | 1351761-44-8 |
| MW: | 443.4 D |
From 128.00€
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GNE-7915
Item number: LKT-G5216.1
LRRK2 inhibitor.
| Keywords: | GNE7915 |
| Application: | LRRK2 inhibitor |
| CAS | 1351761-44-8 |
| MW: | 443.4 D |
From 95.00€
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