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Item number: TGM-T17226-100mg

Description: Vericiguat (BAY1021189) is a potent and orally available guanylate cyclase stimulator. Target: Guanylate cyclase. Smiles: COC(=O)Nc1c(N)nc(nc1N)-c1nn(Cc2ccccc2F)c2ncc(F)cc12. References: Follmann M, et al. Discovery of the Soluble Guanylate Cyclase Stimulator Vericiguat (BAY 1021189) for the Treatment...

Keywords:	BAY1021189
Application:	Targets guanylate cyclase soluble subunit alpha [EC:4.6.1.2] (GUCY1A)
CAS	1350653-20-1
MW:	426.38 D

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Vericiguat

Item number: Cay35253-10

Vericiguat is a stimulator of soluble guanylyl cyclase (sGC). It stimulates the formation of cGMP in CHO cells expressing recombinant rat sGC in the absence and presence of the nitric oxide (NO) donor SNAP (Cay-82250, EC50s = 1,005 and 39 nM, respectively), an effect that can be reversed by the sGC inhibitor ODQ...

Keywords:	BAY-1021189, MK-1242,...
Application:	Soluble guanylyl cyclase stimulator
CAS	1350653-20-1
MW:	426.4 D

From 91.00€ *

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