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Item number: TGM-T21302-100mg

Description: UNC569 (UNC 569) is a selective inhibitor of URAT1, a transporter in the kidney that regulates uric acid excretion from the body. It is also a selective uric acid re-absorption inhibitor. UNC569 could normalize the amount of uric acid excreted by gout patients previously classified as under-excretors....

Keywords:	UNC 569
CAS	1350547-65-7
MW:	396.5 D

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UNC569

Item number: Cay22966-5

UNC569 is a potent inhibitor of the TAM family receptor tyrosine kinases Mer, Axl, and Tyro3 (IC50s = 2.9, 37, and 48 nM, respectively). It has antiproliferative activity in vitro against acute lymphoblastic leukemia (ALL) cells (IC50s = 0.5 and 1.2 µM for 697 and Jurkat cell lines, respectively) and inhibits Mer...

Keywords:	1-[(trans-4-aminocyclohexyl)methyl]-N-butyl-3-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine
Application:	MERTK inhibitor
CAS	1350547-65-7
MW:	396.5 D

From 52.00€ *

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