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Axitinib sulfoxide
Item number: TGM-T21129-1mg
Description: Axitinib sulfoxide is a major metabolite of Axitinib, which is a VEGFR tyrosine kinase inhibitor and may be useful in cancer therapy. Target: Others. Smiles: C(=C/C1=CC=CC=N1)\C=2C=3C(=CC(S(=O)C4=C(C(NC)=O)C=CC=C4)=CC3)NN2. References: Slobbe P, Poot AJ, Haumann R, Schuit RC, Windhorst AD, van Dongen...
| Keywords: | PF-03482595, AG-028458, Axitinib metabolite M12 |
| Application: | Major inactive metabolite |
| CAS | 1347304-18-0 |
| MW: | 402.47 D |
From 151.00€
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Axitinib Sulfoxide
Item number: Cay28042-1
Axitinib sulfoxide is a major inactive metabolite of the tyrosine kinase inhibitor axitinib (Cay-13813). It is formed from axitinib primarily by the cytochrome P450 (CYP) isoform CYP3A4 with minor contributions from CYP3A5 and CYP2C19.Formal Name:...
| Keywords: | N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfinyl]-benzamide |
| Application: | Major inactive metabolite |
| CAS | 1347304-18-0 |
| MW: | 402.5 D |
From 84.00€
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