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GSK343
Item number: Cay14094-1
The histone H3 lysine 27 (H3K27) methyltransferase EZH2 plays an important role in regulating gene expression, and its aberrant activity is linked to the onset and progression of cancer. GSK343 is a cell-permeable EZH2 inhibitor (IC50 = 4 nM) that is 60-fold selective over EZH1 and >1,000-fold selective over other...
| Keywords: | N-[(1,2-dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[2-(4-methyl-1-piperazinyl)-4-pyridinyl]-1... |
| Application: | Cell-permeable EZH2 inhibitor |
| CAS | 1346704-33-3 |
| MW: | 541.7 D |
From 50.00€
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GSK-343
Item number: LKT-G7442.1
GSK-343 is an inhibitor of enhancer of zeste homolog 2 (EZH2) histone methyltransferase (HMT). GSK-343 exhibits anticancer activity, inhibiting cell invasion and cell growth in epithelial ovarian cancer cells.
| Application: | Cell-permeable EZH2 inhibitor |
| CAS | 1346704-33-3 |
| MW: | 541.69 D |
From 77.00€
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