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GSK126
Item number: TGM-T2079-100mg
Description: GSK126 (GSK2816126A) is a excellently specific EZH2 methyltransferase inhibitor ( IC50=9.9 nM). Target: Histone Methyltransferase. Smiles: CC[C@H](C)n1cc(C)c2c(cc(cc12)-c1ccc(nc1)N1CCNCC1)C(=O)NCc1c(C)cc(C)[nH]c1=O. References: Ott HM, et al. A687V EZH2 is a driver of histone H3 lysine 27 (H3K27)...
| Keywords: | GSK2816126A, EZH2 inhibitor |
| Application: | Selective EZH2 methyltransferase inhibitor |
| CAS | 1346574-57-9 |
| MW: | 526.67 D |
From 39.00€
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GSK126
Item number: Cay15415-1
The histone H3 lysine 27 (H3K27) methyltransferase EZH2 plays an important role in regulating gene expression, and its aberrant activity is linked to the onset and progression of cancer. GSK126 is a selective, S-adenosyl-methionine-competitive small molecule inhibitor of EZH2 methyltransferase activity (Ki = 0.57...
| Keywords: | N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-3-methyl-1-[(1S)-1-methylpropyl]-6-[6-(1-piperazinyl)-3-pyridinyl]-... |
| Application: | Selective EZH2 methyltransferase inhibitor |
| CAS | 1346574-57-9 |
| MW: | 526.7 D |
From 86.00€
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GSK126
Item number: LKT-G7340.1
GSK126 is a potent, highly selective, S-adenosyl-methionine-competitive, small-molecule inhibitor of EZH2 methyltransferase activity. GSK126 decreases global H3K27me3 levels.
| Keywords: | GSK-126,... |
| Application: | EZH2 inhibitor |
| CAS | 1346574-57-9 |
| MW: | 526.67 D |
From 87.00€
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