- Search results for 1345982-69-5
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2 products were found matching "1345982-69-5"!
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Item number: TGM-T3978-10mg
Description: Linerixibat (GSK2330672) is a highly effective, nonabsorbable ASBT inhibitor (IC50: 42 ± 3 nM) that can lower glucose in an animal model of type 2 diabetes and demonstrates excellent developability properties. Target: HBV. Smiles:...
Keywords: | Iinerixibat, GSK2330672 |
Application: | Targets solute carrier family 10 (sodium/bile acid cotransporter), member 2 (SLC10A2, ASBT) |
CAS | 1345982-69-5 |
MW: | 546.68 D |
From 76.00€
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Item number: Cay23843-1
GSK2330672 is an inhibitor of the sodium/bile acid and sulfated solute cotransporter (ASBT, IC50s = 42, 2.1, and 1.9 nM for human, mouse, and rat ASBT, respectively). In vivo, GSK2330672 (0.05 mg/kg) stimulates fecal bile acid secretion, reduces hemoglobin A1c (HbA1c) and plasma glucose levels, and increases total...
Keywords: | 3-[[[(3R,5R)-3-butyl-3-ethyl-2,3,4,5-tetrahydro-7-methoxy-1,1-dioxido-5-phenyl-1,4-benzothiazepin-8-yl]methyl]amino]-penta... |
Application: | SLC10A2 / ASBT inhibitor |
CAS | 1345982-69-5 |
MW: | 546.7 D |
From 150.00€
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