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Linerixibat
Linerixibat

Item number: TGM-T3978-10mg

Description: Linerixibat (GSK2330672) is a highly effective, nonabsorbable ASBT inhibitor (IC50: 42 ± 3 nM) that can lower glucose in an animal model of type 2 diabetes and demonstrates excellent developability properties. Target: HBV. Smiles:...
Keywords: Iinerixibat, GSK2330672
Application: Targets solute carrier family 10 (sodium/bile acid cotransporter), member 2 (SLC10A2, ASBT)
CAS 1345982-69-5
MW: 546.68 D
From 76.00€ *
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GSK2330672
GSK2330672

Item number: Cay23843-1

GSK2330672 is an inhibitor of the sodium/bile acid and sulfated solute cotransporter (ASBT, IC50s = 42, 2.1, and 1.9 nM for human, mouse, and rat ASBT, respectively). In vivo, GSK2330672 (0.05 mg/kg) stimulates fecal bile acid secretion, reduces hemoglobin A1c (HbA1c) and plasma glucose levels, and increases total...
Keywords: 3-[[[(3R,5R)-3-butyl-3-ethyl-2,3,4,5-tetrahydro-7-methoxy-1,1-dioxido-5-phenyl-1,4-benzothiazepin-8-yl]methyl]amino]-penta...
Application: SLC10A2 / ASBT inhibitor
CAS 1345982-69-5
MW: 546.7 D
From 150.00€ *
Review