3 products were found matching "1345847-93-9"!
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Altiratinib
Item number: TGM-T2054-100mg
Description: Altiratinib (DCC-2701)(DCC-2701) is a novel c-MET/TIE-2/VEGFR inhibitor, effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling, cell growth and migration as compared with an HGF antagonist in vitro. Target: c-Met/HGFR, FLT, Tie-2, Trk receptor, VEGFR. Smiles:...
| Keywords: | DCC-2701 |
| Application: | Targets proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1] (MET, HGFR) |
| CAS | 1345847-93-9 |
| MW: | 510.46 D |
From 48.00€
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Altiratinib
Item number: Cay18777-5
Altiratinib is a multiple kinase inhibitor, blocking Met, Tie2, VEGF2, TrkA, TrkB, and TrkC with IC50 values of 2.7, 8.0, 9.2, 0.85, 4.6, and 0.83 nM, respectively. It also inhibits several mutant Met isoforms at nanomolar concentrations. Altiratinib inhibits the proliferation of several cancer cell lines in vitro...
| Keywords: | N-[4-[[2-[(cyclopropylcarbonyl)amino]-4-pyridinyl]oxy]-2,5-difluorophenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide |
| Application: | MET / TIE2 / VEGFR2 inhibitor |
| CAS | 1345847-93-9 |
| MW: | 510.5 D |
From 44.00€
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Altiratinib
Item number: LKT-A4777.5
c-MET, Tie-2, VEGFR inhibitor.
| Keywords: | DCC-2701, DP-5164,... |
| Application: | MET / TIE2 / VEGFR2 inhibitor |
| CAS | 1345847-93-9 |
| MW: | 510.46 D |
From 117.00€
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