Description: Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities. Target: Sirtuin. Smiles: O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)[N+]=2C=C(C(N)=O)C=CC2. References: Cantó C, et al. The...

Nicotinamide riboside is a riboside form of nicotinamide (Cay-11127) that is found in trace amounts in yeast-containing and milk-derived products. It is a precursor of NAD+ (Cay-16077) and a source of vitamin B3 (niacin). Nicotinamide riboside increases intracellular and mitochondrial NAD+ content in C2C12, Hepa1.6,...