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AG-370
Item number: TGM-T21784-10mg
Description: AG 370, an indole tyrphostin, is a potent inhibitor of PDGF-induced mitogenesis with an IC50 of 20 µM, and it shows weak inhibition of the EGF receptor. Target: Others. Smiles: C(=C(C(=C(C#N)C#N)N)C#N)C=1C=C2C(=CC1)NC=C2
| CAS | 134036-53-6 |
| MW: | 259.27 D |
From 140.00€
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AG-370
Item number: Cay10010568-5
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which selectively inhibit PTKs of key growth factors such as epidermal growth factor (EGF) or platelet-derived growth factor (PDGF)...
| Keywords: | NSC 651712, 3-amino-4-(1H-indol-5-ylmethylene)-2-pentenetricarbonitrile |
| Application: | PDGF receptor kinase inhibitor |
| CAS | 134036-53-6 |
| MW: | 259.3 D |
From 77.00€
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