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Item number: Cay37332-10

MKC8866 is an inhibitor of inositol-requiring enzyme 1alpha (IRE1alpha) RNase activity (IC50 = 0.29 µM). It inhibits DTT-induced production of the IRE1alpha target protein and transcription factor X-box binding protein 1 (XBP1) in MM.1S multiple myeloma cells (EC50 = 0.52 µM) and XBP1 production induced by...

Keywords:	Inositol-Requiring Enzyme 1alpha Inhibitor 8866, IRE1-IN-8866,...
Application:	IRE1alpha RNase activity inhibitor
CAS	1338934-59-0
MW:	361.4 D

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