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Item number: TGM-T15594-100mg

Description: MKC8866 is a selective IRE1 RNase inhibitor (IC50: 0.29 µM in human vitro). MKC8866 inhibits IRE1 RNase in breast cancer cells leading to the decreased production of pro-tumorigenic factors and it can inhibit prostate cancer (PCa) tumor growth. Target: IRE1. Smiles:...

Application:	IRE1alpha RNase activity inhibitor
CAS	1338934-59-0
MW:	361.35 D

From 78.00€ *

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MKC8866

Item number: Cay37332-10

MKC8866 is an inhibitor of inositol-requiring enzyme 1alpha (IRE1alpha) RNase activity (IC50 = 0.29 µM). It inhibits DTT-induced production of the IRE1alpha target protein and transcription factor X-box binding protein 1 (XBP1) in MM.1S multiple myeloma cells (EC50 = 0.52 µM) and XBP1 production induced by...

Keywords:	Inositol-Requiring Enzyme 1alpha Inhibitor 8866, IRE1-IN-8866,...
Application:	IRE1alpha RNase activity inhibitor
CAS	1338934-59-0
MW:	361.4 D

From 149.00€ *

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