3 products were found matching "1335106-03-0"!

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SR1001
SR1001

Item number: TGM-T5163-100mg

Description: SR 1001 is an inverse agonist for RORalpha/RORgamma (Kis: 172/111 nM). Target: ROR. Smiles: CC(=O)Nc1nc(C)c(s1)S(=O)(=O)Nc1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F. References: Solt LA, et al. Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand. Nature. 2011 Apr 28,472(7344):491-4.
Application: RORalpha and RORgamma inverse agonist
CAS 1335106-03-0
MW: 477.4 D
From 34.00€ *
Review
SR 1001
SR 1001

Item number: Cay10922-1

Retinoic-acid-receptor-related orphan receptors (ROR) alpha and gamma play a key role in the development of T-helper cells that produce interleukin-17 (TH17 cells), a subset of CD4+ T-cells that contribute to the inflammatory process and have been implicated in the pathology of autoimmune diseases. SR 1001 is a...
Keywords: N-(5-(N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)sulfamoyl)-4-methylthiazol-2-yl)acetamide
Application: RORalpha and RORgamma inverse agonist
CAS 1335106-03-0
MW: 477.4 D
From 44.00€ *
Review
SR1001
SR1001

Item number: LKT-S6800.5

RORalpha/gamma inverse agonist.
Application: RORalpha/gamma inverse agonist
CAS 1335106-03-0
MW: 477.4 D
From 86.00€ *
Review