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Item number: TGM-T3998-100mg

Description: Itacitinib (INCB039110) is an orally bioavailable Janus-associated kinase 1 (JAK1) inhibitor with potential antineoplastic activity. Target: JAK. Smiles: Fc1c(ccnc1C(F)(F)F)C(=O)N1CCC(CC1)N1CC(CC#N)(C1)n1cc(cn1)-c1ncnc2[nH]ccc12. References: Bissonnette R, et al. A randomized, double-blind,...

Keywords:	INCB039110, INCB39110
Application:	Targets Janus kinase 1 [EC:2.7.10.2] (JAK1)
CAS	1334298-90-6
MW:	553.51 D

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Itacitinib

Item number: Cay27597-1

Itacitinib is an inhibitor of JAK1. It is greater than 20- and 200-fold selective for JAK1 over JAK2 and JAK3, respectively.Formal Name: 1-[1-[[3-fluoro-2-(trifluoromethyl)-4-pyridinyl]carbonyl]-4-piperidinyl]-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile. CAS Number: 1334298-90-6....

Keywords:	INCB 039110,...
Application:	JAK1 inhibitor
CAS	1334298-90-6
MW:	553.5 D

From 44.00€ *

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Review

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