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Item number: TGM-T12849L-100mg

Description: SAR7334 hydrochloride, a potent and specific inhibitor of TRPC6 (IC50 of 7.9 nM), effectively targets and inhibits the TRPC6 channel. Target: Others. Smiles: Cl.Cl.N[C@@H]1CCCN(C1)[C@@H]1Cc2ccccc2[C@H]1Oc1ccc(cc1Cl)C#N. References: Ilatovskaya DV, et al. The Role of Angiotensin II in Glomerular Volume...

Application:	TRPC6 blocker
CAS	1333207-63-8
MW:	440.79 D

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SAR7334 (hydrochloride)

Item number: Cay28292-1

SAR7334 is a transient receptor potential canonical 6 (TRPC6) channel blocker (IC50 = 7.9 nM). It is selective for TRPC6 over TRPC4 and TRPC5 (IC50s = 282 and 226 nM, respectively). SAR7334 (0.2-1 µM) blocks TRPC6-dependent hypoxia-induced vasoconstriction in isolated perfused and ventilated mouse lung. It also...

Keywords:	4-[[(1R,2R)-2-[(3R)-3-amino-1-piperidinyl]-2,3-dihydro-1H-inden-1-yl]oxy]-3-chloro-benzonitrile, dihydrochloride
Application:	TRPC6 blocker
CAS	1333207-63-8
MW:	440.8 D

From 52.00€ *

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