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GSK2194069
GSK2194069

Item number: TGM-T15429-2mg

Description: GSK2194069 is an active beta-keto reductase (KR)-specific inhibitor of fatty acid synthase (FASN) with an IC50 of 7.7 nM in an assay for the detection of released CoA.GSK2194069 inhibits the proliferation of FAS in cancer cells through the action of acetoacetyl-coenzyme A and NADPH. Target: Others,...
Application: FASN inhibitor
CAS 1332331-08-4
MW: 428.48 D
148.00€ *
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GSK2194069
GSK2194069

Item number: Cay20022-5

GSK2194069 is an inhibitor of fatty acid synthase (FASN) with an IC50 value of 7.7 nM in an assay detecting released CoA. It is a competitive inhibitor that is selective for the KR domain over the KS domain of FASN, with IC50 values of 29 and >10,000 nM, respectively, in vitro. GSK2194069 decreases incorporation of...
Keywords: 4-[4-(5-benzofuranyl)phenyl]-5-[[(3S)-1-(cyclopropylcarbonyl)-3-pyrrolidinyl]methyl]-2,4-dihydro-3H-1,2,4-triazol-3-one
Application: FASN inhibitor
CAS 1332331-08-4
MW: 428.5 D
From 44.00€ *
Review