Description: Rifampicin (Rifamycin AMP) is a broad-spectrum antibiotic. Rifampicin has a strong antibacterial effect against Mycobacterium tuberculosis and is also effective against gram-positive and gram-negative bacteria and viruses. Target: Antifection, Antibacterial, Antibiotic, DNA/RNA Synthesis, Influenza...

Rifampicin is a rifamycin antibiotic and inhibitor of bacterial RNA polymerase (IC50 = 0.01 µg/ml for the E. coli enzyme). It inhibits the growth of M. tuberculosis H37Rv in mouse peritoneal macrophages (MIC = 0.8 µg/ml) as well as clinical isolates of various species of Staphylococcus, Streptococcus, Haemophilus,...

Semisynthetic antibiotic. Antibacerial (tuberculostatic). Inhibits RNA synthesis via RNA Polymerase binding. Specifically inhibits DNA-dependent RNA polymerase in bacteria by forming an inactive complex. Does not affect mammalian RNA polymerase. Synonyms: 3-[[4-Methyl-1-piperazin-yl)imino]methyl]rifamycin, Rifampin,...

Ansamycin, bacterial DNA-dependent RNA polymerase inhibitor, RNA synthesis inhibitor.