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Lipid-based Drug Delivery Tools

Item number: Cay35786-10

YSK05 is an ionizable cationic amino lipid (apparent pKa = ~6.5) that has been used in combination with other lipids in the formation of liposomes and lipid nanoparticles (LNPs). Administration of cyclic di-GMP (Cay-17144) in YSK05-containing liposomes increases serum levels of IFN-beta, IFN-gamma, IL-6, and...

Keywords:	1-methyl-4,4-bis[(9Z,12Z)-9,12-octadecadien-1-yloxy]-piperidine
Application:	Ionizable amino lipid, LNP formation
CAS	1318793-78-0
MW:	628.1 D

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YSK 05

Item number: TGM-T74553-2mg

Description: YSK 05, a pH-sensitive cationic lipid, enhances the intracellular trafficking of non-viral vectors, significantly improves gene silencing and hemolytic activities in its modified form YSK 05-MEND, and effectively overcomes the suppression of endosomal escape caused by PEGylation, thereby enhancing siRNA...

CAS	1318793-78-0
MW:	628.07 D

67.00€ *

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