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LM10
LM10

Item number: TGM-T4410-100mg

Description: Selective tryptophan 2, 3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 µM for human and mouse TDO, respectively). Exhibits selectivity for TDO over IDO, MAO-A, MAO-B, and a panel of receptors and transporters. Reduces growth of TDO-expressing P815 mastocytoma tumors in mice. Orally...
Application: TDO inhibitor
CAS 1316695-35-8
MW: 229.21 D
From 32.00€ *
Review
LM-10
LM-10

Item number: Cay36291-10

LM-10 is an inhibitor of tryptophan 2,3-dioxygenase (TDO, IC50 = 2 µM). It is selective for TDO over indoleamine 2,3-dioxygenase (IDO), monoamine oxidase A (MAO-A), and MAO-B, as well as a panel of various receptors and transporters, at 10 µM. LM-10 (1 mg/ml in the drinking water) reverses tumoral immune resistance...
Keywords: 6-fluoro-3-[(1E)-2-(2H-tetrazol-5-yl)ethenyl]-1H-indole
Application: TDO inhibitor
CAS 1316695-35-8
MW: 229.2 D
From 83.00€ *
Review