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RU-505
RU-505

Item number: TGM-T24743-10mg

Description: RU-505 is an interaction inhibitor of Abeta-fibrinogen that acts by rescuing altered thrombosis and cognitive decline in Alzheimer's disease mice. Target: Others. Smiles: C(C)(C)(C)C1=NN2C(=CC(C(N(CC3=CC=CC=C3)CCN(C)C)=O)=NC2=C1)C4=CC=C(F)C=C4. References: Ahn HJ, Glickman JF, Poon KL, Zamolodchikov D,...
Keywords: RU 505, RU505
Application: Abeta-fibrinogen interaction inhibitor
CAS 1314206-29-5
MW: 473.58 D
From 140.00€ *
Review
RU-505
RU-505

Item number: Cay16445-1

RU-505 is an inhibitor of the interaction between amyloid-beta (Abeta) and fibrinogen, with a higher efficacy for inhibiting monomeric forms of Abeta bound to fibrinogen over oligomeric forms. In vitro, RU-505 (20 µM) normalizes fibrin clot formation that is disrupted when fibrinogen is bound to Abeta42. RU-505 (35...
Keywords: N-[2-(dimethylamino)ethyl]-2-(1,1-dimethylethyl)-7-(4-fluorophenyl)-N-(phenylmethyl)-pyrazolo[1,5-a]pyrimidine-5-carboxamide
Application: Abeta-fibrinogen interaction inhibitor
CAS 1314206-29-5
MW: 473.6 D
From 77.00€ *
Review