2 products were found matching "1313881-70-7"!

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Item number: TGM-T3467-100mg

Description: Miransertib (ARQ-092) is an orally bioavailable, selective, and potent allosteric Akt inhibitor. Target: Akt, Parasite. Smiles: Nc1ncccc1-c1nc2ccc(nc2n1-c1ccc(cc1)C1(N)CCC1)-c1ccccc1. References: Yu Y, et al. PLoS One. 2015, 10(10):e20140479.

Keywords:	AKT inhibitor 2, ARQ-092
Application:	Targets RAC serine/threonine-protein kinase [EC:2.7.11.1] (AKT)
CAS	1313881-70-7
MW:	432.52 D

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ARQ 092

Item number: Cay21388-1

ARQ 092 is an allosteric, orally bioavailable, pan-Akt inhibitor (IC50s = 5.0, 4.5, and 16 nM for Akt1, Akt2, and Akt3, respectively). It is selective for Akt isoforms over a panel of 303 other kinases. ARQ 092 binds inactive Akt and prevents membrane localization and full Akt activation. It also directly inhibits...

Keywords:	3-[3-[4-(1-aminocyclobutyl)phenyl]-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl]-2-pyridinamine
Application:	AKT inhibitor
CAS	1313881-70-7
MW:	432.5 D

From 60.00€ *

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