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Savolitinib
Item number: TGM-TQ0210-100mg
Description: Savolitinib (Volitinib) (AZD-6094) is an effective, selective, and orally bioavailable c-Met inhibitor (IC50s: 5 nM/3 nM for c-Met/p-Met). Target: c-Met/HGFR. Smiles: C[C@@H](c1ccc2nccn2c1)n1nnc2ncc(nc12)-c1cnn(C)c1. References: Jia H, et al. Discovery of...
| Keywords: | Volitinib, AZD-6094, HMPL-504 |
| Application: | Targets proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1] (MET, HGFR) |
| CAS | 1313725-88-0 |
| MW: | 345.36 D |
From 42.00€
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Savolitinib
Item number: Cay33332-1
Savolitinib is an inhibitor of c-Met (IC50 = 5 nM). It is selective for c-Met over a panel of 274 other kinases at 1 µM. Savolitinib inhibits c-Met autophosphorylation in NCI H441 human non-small cell lung cancer (NSCLC) cells (IC50 = 3 nM). It also inhibits proliferation of NCI H441 cells induced by HGF (Cay-32052,...
| Keywords: | AZD6094, HMPL-504, Volitinib,... |
| Application: | c-Met inhibitor |
| CAS | 1313725-88-0 |
| MW: | 345.4 D |
From 98.00€
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Volitinib
Item number: LKT-V574451.1
c-Met inhibitor.
| Keywords: | Savolitinib, HMPL 504, HMPL0-504, HMPL504, AZD-6094, AZD 6094, AZD6094 |
| Application: | c-Met inhibitor |
| CAS | 1313725-88-0 |
| MW: | 345.37 D |
From 140.00€
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