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L-655708
Item number: TGM-TQ0151-10mg
Description: L-655708 is a selective and highly potent GABAA receptor reverse agonist with a Ki value of 0.45 nM. Target: GABA Receptor. Smiles: [H][C@@]12CCCN1C(=O)c1cc(OC)ccc1-n1cnc(C(=O)OCC)c21. References: Saab BJ, et al. Short-term memory impairment after isoflurane in mice is prevented by the alpha5...
| Application: | Nootropic GABA(A) receptor subunit alpha-5 ligand |
| CAS | 130477-52-0 |
| MW: | 341.36 D |
From 76.00€
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L-655,708
Item number: Cay30322-10
L-655,708 is a ligand for alpha5 subunit-containing GABAA receptors that has nootropic activity. It selectively binds to alpha5 subunit-containing GABAA receptors over alpha1, alpha2, or alpha3 subunit-containing receptors (Kis = 1, 70, 48, and 31 nM, respectively, for recombinant human receptors). L-655,708 (10 nM)...
| Keywords: | (13aS)-11,12,13,13a-tetrahydro-7-methoxy-9-oxo-9H-imidazo[1,5-a]pyrrolo[2,1-c][1,4]benzodiazepine-1-carboxylic acid, ethyl... |
| Application: | Nootropic GABA(A) receptor subunit alpha-5 ligand |
| CAS | 130477-52-0 |
| MW: | 341.4 D |
From 142.00€
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