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Item number: TGM-T7100-100mg

Description: PLX5622 is a highly selective, brain-penetrant, and orally active CSF1R inhibitor. Target: c-Fms, CSF-1R. Smiles: COc1ncc(F)cc1CNc1ccc(Cc2c[nH]c3ncc(C)cc23)c(F)n1. References: Rosin JM, Vora SR, Kurrasch DM.Depletion of embryonic microglia using the CSF1R inhibitor PLX5622 has adverse sex-specific...

Keywords:	PLX-5622
Application:	CSF1R inhibitor
CAS	1303420-67-8
MW:	395.41 D

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PLX5622

Item number: Cay28927-1

PLX5622 is a brain-penetrant inhibitor of the colony stimulating factor 1 receptor (CSF1R, IC50 = 0.016 µM). It is selective for CSF1R over FMS-related tyrosine kinase 3 (FLT3), Kit, Aurora C, and kinase insert domain receptor (VEGFR2, IC50s = 0.39, 0.86, 1, and 1.1 µM, respectively) and is greater than 100-fold...

Keywords:	5-fluoro-N-[6-fluoro-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-2-pyridinyl]-2-methoxy-3-pyridinemethanamine
Application:	CSF1R inhibitor
CAS	1303420-67-8
MW:	395.4 D

From 35.00€ *

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